Specific anti‐glioma targeted‐delivery strategy of engineered small extracellular vesicles dual‐functionalised by Angiopep‐2 and TAT peptides

Specific anti‐glioma targeted‐delivery strategy of engineered small extracellular vesicles dual‐functionalised by Angiopep‐2 and TAT peptides

Abstract Glioma is one of the primary malignant brain tumours in adults, with a poor prognosis. Pharmacological reagents targeting glioma are limited to achieve the desired therapeutic effect due to the presence of blood‐brain barrier (BBB). Effectively crossing the BBB and specifically targeting to...

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Bibliographic Details
Main Authors: Zhanchi Zhu, Yuanxin Zhai, Ying Hao, Quanwei Wang, Fang Han, Wenlong Zheng, Jing Hong, Leisha Cui, Wei Jin, Sancheng Ma, Lingyan Yang, Guosheng Cheng
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Journal of Extracellular Vesicles
Subjects:
Angiopep‐2
blood‐brain barrier
dual‐targeting
glioma
small extracellular vesicles
TAT
Online Access:https://doi.org/10.1002/jev2.12255

Internet

https://doi.org/10.1002/jev2.12255

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