Preparation and Evaluation of the ZnO NP–Ampicillin/Sulbactam Nanoantibiotic: Optimization of Formulation Variables Using RSM Coupled GA Method and Antibacterial Activities

Preparation and Evaluation of the ZnO NP–Ampicillin/Sulbactam Nanoantibiotic: Optimization of Formulation Variables Using RSM Coupled GA Method and Antibacterial Activities

Nanoparticles (NPs) possessing antibacterial activity represent an effective way of overcoming bacterial resistance. In the present work, we report a novel formulation of a nanoantibiotic formed using Ampicillin/sulbactam (Ams) and a zinc oxide nanoparticle (ZnO NP). ‘ZnO NP−Ams&...

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Bibliographic Details
Main Authors: Nidhi Sharma, Vineeta Singh, Asheesh Kumar Pandey, Bhartendu Nath Mishra, Maria Kulsoom, Nandita Dasgupta, Saif Khan, Hesham A. El-Enshasy, Shafiul Haque
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Biomolecules
Subjects:
<i>klebsiella pneumoniae</i>
ampicillin/sulbactam
zno nanoparticle
response surface methodology
genetic algorithm
Online Access:https://www.mdpi.com/2218-273X/9/12/764

Internet

https://www.mdpi.com/2218-273X/9/12/764

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