Natural variation of the amino-terminal glutamine-rich domain in Drosophila argonaute2 is not associated with developmental defects.

Natural variation of the amino-terminal glutamine-rich domain in Drosophila argonaute2 is not associated with developmental defects.

The Drosophila argonaute2 (ago2) gene plays a major role in siRNA mediated RNA silencing pathways. Unlike mammalian Argonaute proteins, the Drosophila protein has an unusual amino-terminal domain made up largely of multiple copies of glutamine-rich repeats (GRRs). We report here that the ago2 locus...

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Bibliographic Details
Main Authors: Daniel Hain, Brian R Bettencourt, Katsutomo Okamura, Tibor Csorba, Wibke Meyer, Zhigang Jin, Jason Biggerstaff, Haruhiko Siomi, Gyorgy Hutvagner, Eric C Lai, Michael Welte, H-Arno J Müller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3002974?pdf=render

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http://europepmc.org/articles/PMC3002974?pdf=render

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