Immunostimulatory property of a synthetic peptide belonging to the soluble ATP diphosphohydro-lase isoform (SmATPDase 2) and immunolocalisation of this protein in the Schistosoma mansoni egg

Immunostimulatory property of a synthetic peptide belonging to the soluble ATP diphosphohydro-lase isoform (SmATPDase 2) and immunolocalisation of this protein in the Schistosoma mansoni egg

A peptide (SmB2LJ; r175-194) that belongs to a conserved domain from Schistosoma mansoni SmATPDase 2 and is shared with potato apyrase, as predicted by in silico analysis as antigenic, was synthesised and its immunostimulatory property was analysed. When inoculated in BALB/c mice, this peptide induc...

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Bibliographic Details
Main Authors: Rita Gabriela Pedrosa Ribeiro Mendes, Michélia Antônia do Nascimento Gusmão, Ana Carolina Ribeiro Gomes Maia, Michelle de Lima Detoni, Gabriane Nascimento Porcino, Thais Vieira Soares, Maria Aparecida Juliano, Luiz Juliano, Paulo Marcos Zech Coelho, Henrique Leonel Lenzi, Priscila Faria-Pinto, Eveline Gomes Vasconcelos
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2011-11-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Schistosoma mansoni
NTPDase
potato apyrase
peptide
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000700005&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000700005&lng=en&tlng=en

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