Gene editing with ‘pencil’ rather than ‘scissors’ in human pluripotent stem cells

Gene editing with ‘pencil’ rather than ‘scissors’ in human pluripotent stem cells

Abstract Owing to the advances in genome editing technologies, research on human pluripotent stem cells (hPSCs) have recently undergone breakthroughs that enable precise alteration of desired nucleotide bases in hPSCs for the creation of isogenic disease models or for autologous ex vivo cell therapy...

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Bibliographic Details
Main Authors: Ju-Chan Park, Mihn Jeong Park, Seung-Yeon Lee, Dayeon Kim, Keun-Tae Kim, Hyeon-Ki Jang, Hyuk-Jin Cha
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Stem Cell Research & Therapy
Subjects:
Human pluripotent stem cells
Disease modeling
Ex vivo therapy
Isogenic pair
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Online Access:https://doi.org/10.1186/s13287-023-03394-5

Internet

https://doi.org/10.1186/s13287-023-03394-5

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