Protective effects of compound M01 on retinal ganglion cells in experimental anterior ischemic optic neuropathy by inhibiting TXNIP/NLRP3 inflammasome pathway

Protective effects of compound M01 on retinal ganglion cells in experimental anterior ischemic optic neuropathy by inhibiting TXNIP/NLRP3 inflammasome pathway

Apoptotic death of retinal ganglion cells (RGCs) is a common pathologic feature in different types of optic neuropathy, including ischemic optic neuropathy and glaucoma, ultimately leading to irreversible visual function loss. Potent and effective protection against RGC death is determinative in dev...

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Bibliographic Details
Main Authors: Jia-Ying Chien, Jhih-Wei Ciou, Yun Yen, Shun-Ping Huang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Anterior ischemic optic neuropathy. M01
Retinal ganglion cell
Apoptosis
Demyelination
Microglial
Nrf2
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223016591

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http://www.sciencedirect.com/science/article/pii/S0753332223016591

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