Insight into the on/off switch that regulates expression of the MSMEG-3762/63 efflux pump in Mycobacterium smegmatis

Insight into the on/off switch that regulates expression of the MSMEG-3762/63 efflux pump in Mycobacterium smegmatis

Abstract Drug resistance is one of the most difficult challenges facing tuberculosis (TB) control. Drug efflux is among the mechanisms leading to drug resistance. In our previous studies, we partially characterized the ABC-type MSMEG-3762/63 efflux pump in Mycobacterium smegmatis, which shares high...

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Bibliographic Details
Main Authors: Nicoletta Campolattano, Gianluca D’Abrosca, Luigi Russo, Barbara De Siena, Milena Della Gala, Ida De Chiara, Rosangela Marasco, Aaron Goff, Simon J. Waddell, Margherita Sacco, Lidia Muscariello
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47695-4

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https://doi.org/10.1038/s41598-023-47695-4

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