Grade 2, 3 and Dedifferentiated Chondrosarcomas: A Comparative Study of Isocitrate Dehydrogenase-Mutant and Wild-Type Tumors with Implications for Prognosis and Therapy

Grade 2, 3 and Dedifferentiated Chondrosarcomas: A Comparative Study of Isocitrate Dehydrogenase-Mutant and Wild-Type Tumors with Implications for Prognosis and Therapy

Background: Grade 2 and 3 and dedifferentiated chondrosarcomas (CS) are frequently associated with isocitrate dehydrogenase (<i>IDH</i>) mutations and often exhibit a poor clinical outcome. Treatment is limited mainly to surgery. Defining <i>IDH</i> status (wild type (WT) and...

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Bibliographic Details
Main Authors: Karen Schoedel, Tanya Heim, Anette Duensing, Ines Lohse, Laura Presutti, Rebekah Belayneh, Sumail Bhogal, Anya Singh-Varma, Alexander Chang, Uma Chandran, Daniel Marker, Heather Szabo-Rogers, Kurt Weiss
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
chondrosarcoma
RNA sequencing
isocitrate dehydrogenase
genomics
Online Access:https://www.mdpi.com/2072-6694/16/2/247

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https://www.mdpi.com/2072-6694/16/2/247

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