Investigating auranofin for the treatment of infected diabetic pressure ulcers in mice and dermal toxicity in pigs

Abstract Bacterial infection of pressure ulcers (PUs) are a notable source of hospitalization for individuals with diabetes. This study evaluated the safety profile and efficacy of auranofin to treat diabetic PUs infected with methicillin-resistant Staphylococcus aureus (MRSA). PUs were infected wit...

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Bibliographic Details
Main Authors: Haroon Mohammad, Nader S. Abutaleb, Alexandra M. Dieterly, L. Tiffany Lyle, Mohamed N. Seleem
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90360-x