Apical-out airway organoids as a platform for studying viral infections and screening for antiviral drugs

Apical-out airway organoids as a platform for studying viral infections and screening for antiviral drugs

Abstract Airway organoids are polarized 3D epithelial structures that recapitulate the organization and many of the key functions of the in vivo tissue. They present an attractive model that can overcome some of the limitations of traditional 2D and Air–Liquid Interface (ALI) models, yet the limited...

Full description

Bibliographic Details
Main Authors: Georgios Stroulios, Tyler Brown, Giulia Moreni, Douglas Kondro, Alessandro Dei, Allen Eaves, Sharon Louis, Juan Hou, Wing Chang, Dasja Pajkrt, Katja C. Wolthers, Adithya Sridhar, Salvatore Simmini
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11700-z

Internet

https://doi.org/10.1038/s41598-022-11700-z

Similar Items