Apical-out airway organoids as a platform for studying viral infections and screening for antiviral drugs
Abstract Airway organoids are polarized 3D epithelial structures that recapitulate the organization and many of the key functions of the in vivo tissue. They present an attractive model that can overcome some of the limitations of traditional 2D and Air–Liquid Interface (ALI) models, yet the limited...
Main Authors: | Georgios Stroulios, Tyler Brown, Giulia Moreni, Douglas Kondro, Alessandro Dei, Allen Eaves, Sharon Louis, Juan Hou, Wing Chang, Dasja Pajkrt, Katja C. Wolthers, Adithya Sridhar, Salvatore Simmini |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-11700-z |
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