Transfer of H2O2 from Mitochondria to the endoplasmic reticulum via Aquaporin-11
Some aquaporins (AQPs) can transport H2O2 across membranes, allowing redox signals to proceed in and between cells. Unlike other peroxiporins, human AQP11 is an endoplasmic reticulum (ER)-resident that can conduit H2O2 to the cytosol. Here, we show that silencing Ero1α, an ER flavoenzyme that genera...
Main Authors: | Ilaria Sorrentino, Mauro Galli, Iria Medraño-Fernandez, Roberto Sitia |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-09-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231722001823 |
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