Multivariate Meta-Analysis of Genetic Association Studies: A Simulation Study.

In a meta-analysis with multiple end points of interests that are correlated between or within studies, multivariate approach to meta-analysis has a potential to produce more precise estimates of effects by exploiting the correlation structure between end points. However, under random-effects assump...

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Bibliographic Details
Main Authors: Binod Neupane, Joseph Beyene
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4509672?pdf=render