The Many Faces of G Protein-Coupled Receptor 143, an Atypical Intracellular Receptor

The Many Faces of G Protein-Coupled Receptor 143, an Atypical Intracellular Receptor

GPCRs transform extracellular stimuli into a physiological response by activating an intracellular signaling cascade initiated via binding to G proteins. Orphan G protein-coupled receptors (GPCRs) hold the potential to pave the way for development of new, innovative therapeutic strategies. In this r...

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Bibliographic Details
Main Authors: Beatriz Bueschbell, Prashiela Manga, Anke C. Schiedel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
orphan receptors
GPCRs (G protein-coupled receptors)
GPR143
ocular albinism type 1 (OA1)
melanosome
intracellular GPCR
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.873777/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.873777/full

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