Prevalence of TP53 gene Pro72Arg (rs1042522) single nucleotide polymorphism among Egyptian breast cancer patients

Abstract Background The P53 protein has an essential role in several cellular processes, including DNA repair, apoptosis, and cell cycle arrest. The pathophysiology of many cancer types has frequently been linked to polymorphisms in the TP53 locus. Over 200 single nucleotide polymorphisms (SNPs) hav...

Full description

Bibliographic Details
Main Authors: Shaza Ahmed, Gehan Safwat, Mohamed M. Moneer, AbdelWahab El Ghareeb, Ahmed A. El Sherif, Samah A. Loutfy
Format: Article
Language:English
Published: SpringerOpen 2023-03-01
Series:Egyptian Journal of Medical Human Genetics
Online Access:https://doi.org/10.1186/s43042-023-00405-1