Prevalence of TP53 gene Pro72Arg (rs1042522) single nucleotide polymorphism among Egyptian breast cancer patients
Abstract Background The P53 protein has an essential role in several cellular processes, including DNA repair, apoptosis, and cell cycle arrest. The pathophysiology of many cancer types has frequently been linked to polymorphisms in the TP53 locus. Over 200 single nucleotide polymorphisms (SNPs) hav...
Main Authors: | Shaza Ahmed, Gehan Safwat, Mohamed M. Moneer, AbdelWahab El Ghareeb, Ahmed A. El Sherif, Samah A. Loutfy |
---|---|
Format: | Article |
Language: | English |
Published: |
SpringerOpen
2023-03-01
|
Series: | Egyptian Journal of Medical Human Genetics |
Online Access: | https://doi.org/10.1186/s43042-023-00405-1 |
Similar Items
-
TP53 Gene 72 Arg/Pro (rs1042522) single nucleotide polymorphism increases the risk and the severity of chronic lymphocytic leukemia
by: Asma Ounalli, et al.
Published: (2023-10-01) -
The association of TP53 (Arg72Pro) rs1042522 C>G polymorphism and colorectal cancer susceptibility in Duhok individuals
by: Najat Taher Mahmood ,Dilan Jasim Khalil ,Salar Saadi Hussain ,Ibrahim Hasan Mustafa ,Farida Fariq Nerweyi
Published: (2023-08-01) -
Mathematical analysis of the effect of Pro72Arg polymorphism in the TP53 gene on the emergence and progression of POAG
by: S.Iu. Mogilevskyy, et al.
Published: (2016-12-01) -
The p53 codon 72 polymorphism (rs1042522) is associated with proliferative vitreoretinopathy: the Retina 4 Project.
by: Pastor-Idoate, S, et al.
Published: (2013) -
The Association between Single Nucleotide Polymorphisms rs1042522 and rs1642785 in the TP53 gene and Acute Myeloid leukemia in a sample of the Baghdad/ Iraq population
by: Hadeel Hameed Dawood, et al.
Published: (2024-03-01)