Overexpression of syndecan-1, MUC-1, and putative stem cell markers in breast cancer leptomeningeal metastasis: a cerebrospinal fluid flow cytometry study

Overexpression of syndecan-1, MUC-1, and putative stem cell markers in breast cancer leptomeningeal metastasis: a cerebrospinal fluid flow cytometry study

Abstract Background Cancer is a mosaic of tumor cell subpopulations, where only a minority is responsible for disease recurrence and cancer invasiveness. We focused on one of the most aggressive circulating tumor cells (CTCs) which, from the primitive tumor, spreads to the central nervous system (CN...

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Bibliographic Details
Main Authors: Iole Cordone, Serena Masi, Valentina Summa, Mariantonia Carosi, Antonello Vidiri, Alessandra Fabi, Alessia Pasquale, Laura Conti, Immacolata Rosito, Carmine Maria Carapella, Veronica Villani, Andrea Pace
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Leptomeningeal metastasis
Flow cytometry
Circulating tumor cells
Cancer stem cell
Prognosis
Online Access:http://link.springer.com/article/10.1186/s13058-017-0827-4

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http://link.springer.com/article/10.1186/s13058-017-0827-4

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