Spatial profiling of cancer-associated fibroblasts of sporadic early onset colon cancer microenvironment

Abstract The incidence of sporadic early-onset colon cancer (EOCC) has increased worldwide. The molecular mechanisms in the tumor and the tumor microenvironment (TME) in EOCC are not fully understood. The aim of this study is to unravel unique spatial transcriptomic and proteomic profiles in tumor e...

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Bibliographic Details
Main Authors: Satoru Furuhashi, Matias A. Bustos, Shodai Mizuno, Suyeon Ryu, Yalda Naeini, Anton J. Bilchik, Dave S. B. Hoon
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00474-w