Identification of biomarkers predictive of metastasis development in early-stage colorectal cancer using network-based regularization

Identification of biomarkers predictive of metastasis development in early-stage colorectal cancer using network-based regularization

Abstract Colorectal cancer (CRC) is the third most common cancer and the second most deathly worldwide. It is a very heterogeneous disease that can develop via distinct pathways where metastasis is the primary cause of death. Therefore, it is crucial to understand the molecular mechanisms underlying...

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Bibliographic Details
Main Authors: Carolina Peixoto, Marta B. Lopes, Marta Martins, Sandra Casimiro, Daniel Sobral, Ana Rita Grosso, Catarina Abreu, Daniela Macedo, Ana Lúcia Costa, Helena Pais, Cecília Alvim, André Mansinho, Pedro Filipe, Pedro Marques da Costa, Afonso Fernandes, Paula Borralho, Cristina Ferreira, João Malaquias, António Quintela, Shannon Kaplan, Mahdi Golkaram, Michael Salmans, Nafeesa Khan, Raakhee Vijayaraghavan, Shile Zhang, Traci Pawlowski, Jim Godsey, Alex So, Li Liu, Luís Costa, Susana Vinga
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Bioinformatics
Subjects:
Colorectal cancer
Classification
Biomarker selection
Regularization
iTwiner
Online Access:https://doi.org/10.1186/s12859-022-05104-z

Internet

https://doi.org/10.1186/s12859-022-05104-z

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