Prokineticin System Is a Pharmacological Target to Counteract Pain and Its Comorbid Mood Alterations in an Osteoarthritis Murine Model

Prokineticin System Is a Pharmacological Target to Counteract Pain and Its Comorbid Mood Alterations in an Osteoarthritis Murine Model

Osteoarthritis (OA) is the most prevalent joint disease associated with chronic pain. OA pain is often accompanied by mood disorders. We addressed the role of the Prokineticin (PK) system in pain and mood alterations in a mice OA model induced with monosodium iodoacetate (MIA). The effect of a PK an...

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Bibliographic Details
Main Authors: Giulia Galimberti, Giada Amodeo, Giulia Magni, Benedetta Riboldi, Gianfranco Balboni, Valentina Onnis, Stefania Ceruti, Paola Sacerdote, Silvia Franchi
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
prokineticins
osteoarthritis pain
neuroinflammation
anxiety
depression
Online Access:https://www.mdpi.com/2073-4409/12/18/2255

Internet

https://www.mdpi.com/2073-4409/12/18/2255

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