Voltage-gated potassium channel proteins and stereoselective S-nitroso-l-cysteine signaling

Voltage-gated potassium channel proteins and stereoselective S-nitroso-l-cysteine signaling

S-nitroso-l-cysteine (L-CSNO) behaves as a ligand. Its soluble guanylate cyclase–independent (sGC-independent) effects are stereoselective — that is, not recapitulated by S-nitroso-d-cysteine (D-CSNO) — and are inhibited by chemical congeners. However, candidate L-CSNO receptors have not been identi...

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Bibliographic Details
Main Authors: Benjamin Gaston, Laura Smith, Jürgen Bosch, James Seckler, Diana Kunze, Janna Kiselar, Nadzeya Marozkina, Craig A. Hodges, Patrick Wintrobe, Kellen McGee, Tatiana S. Morozkina, Spencer T. Burton, Tristan Lewis, Timothy Strassmaier, Paulina Getsy, James N. Bates, Stephen J. Lewis
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-09-01
Series:JCI Insight
Subjects:
Cell biology
Online Access:https://doi.org/10.1172/jci.insight.134174

Internet

https://doi.org/10.1172/jci.insight.134174

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