The Link between Mitochondrial Dysfunction and Sarcopenia: An Update Focusing on the Role of Pyruvate Dehydrogenase Kinase 4

Sarcopenia, defined as a progressive loss of muscle mass and function, is typified by mitochondrial dysfunction and loss of mitochondrial resilience. Sarcopenia is associated not only with aging, but also with various metabolic diseases characterized by mitochondrial dyshomeostasis. Pyruvate dehydro...

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Bibliographic Details
Main Authors: Min-Ji Kim, Ibotombi Singh Sinam, Zerwa Siddique, Jae-Han Jeon, In-Kyu Lee
Format: Article
Language:English
Published: Korean Diabetes Association 2023-03-01
Series:Diabetes & Metabolism Journal
Subjects:
Online Access:http://e-dmj.org/upload/pdf/dmj-2022-0305.pdf