Immunization with Hexon modified adenoviral vectors integrated with gp83 epitope provides protection against Trypanosoma cruzi infection.

Trypanosoma cruzi is the causative agent of Chagas disease. Chagas disease is an endemic infection that affects over 8 million people throughout Latin America and now has become a global challenge. The current pharmacological treatment of patients is unsuccessful in most cases, highly toxic, and no...

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Bibliographic Details
Main Authors: Anitra L Farrow, Girish Rachakonda, Linlin Gu, Valentina Krendelchtchikova, Pius N Nde, Siddharth Pratap, Maria F Lima, Fernando Villalta, Qiana L Matthews
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4140675?pdf=render