Ultrasound-Mediated Gene Delivery with Cationic Versus Neutral Microbubbles: Effect of DNA and Microbubble Dose on In Vivo Transfection Efficiency

<p><b>Objective</b>: To assess the effect of varying microbubble (MB) and DNA doses on the overall and comparative efficiencies of ultrasound (US)-mediated gene delivery (UMGD) to murine hindlimb skeletal muscle using cationic versus neutral MBs.</p><p><b>Material...

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Bibliographic Details
Main Author: Cedric M. Panje, David S. Wang, Marybeth A. Pysz, Ramasamy Paulmurugan, Ying Ren, Francois Tranquart, Lu Tian, J&#252;rgen K. Willmann
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:Theranostics
Online Access:http://www.thno.org/v02p1078.htm