Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations

<p>Abstract</p> <p>Background</p> <p>Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumour necrosis factor cytokine family that induces apoptosis upon binding to its death domain containing receptors, TRAIL receptor 1 (DR4) and TRAIL...

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Main Authors: Hussain Azhar R, Al-Dayel Fouad, Alhomoud Samar, Ashari Luai H, Abduljabbar Alaa, Al-Sanea Nasser, George Thara, Qadri Zeeshan, Abubaker Jehad, Prabhakaran Sarita E, Bavi Prashant, Uddin Shahab, Al-Kuraya Khawla S
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/203