Enhancing immunotherapy outcomes by targeted remodeling of the tumor microenvironment via combined cGAS-STING pathway strategies

Enhancing immunotherapy outcomes by targeted remodeling of the tumor microenvironment via combined cGAS-STING pathway strategies

Immune checkpoint inhibitors (ICIs) represent a groundbreaking advance in the treatment of malignancies such as melanoma and non-small cell lung cancer, showcasing substantial therapeutic benefits. Nonetheless, the efficacy of ICIs is limited to a small subset of patients, primarily benefiting those...

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Bibliographic Details
Main Authors: Mingqing Huang, Zhuocen Cha, Rui Liu, Mengping Lin, Naif Abdul Gafoor, Tong Kong, Fei Ge, Wenlin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Immunology
Subjects:
cGAS-STING
hot tumor
tumor immunology
immune checkpoint inhibitor (ICI)
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1399926/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1399926/full

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