Design and optimization of DPC-crosslinked HPβCD nanosponges for entrectinib oral delivery: formulation, characterization, and pharmacokinetic studies

Abstract Background In advanced or metastatic cancers characterized by specific genetic alterations, heightened growth and resistance to conventional therapies are common. Targeted treatments like entrectinib (ENT) precisely inhibit aberrant signaling pathways, potentially enhancing outcomes. The ob...

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Xehetasun bibliografikoak
Egile Nagusiak: Konda Sri Chaya Reddy, Darna Bhikshapathi
Formatua: Artikulua
Hizkuntza:English
Argitaratua: SpringerOpen 2024-08-01
Saila:Future Journal of Pharmaceutical Sciences
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1186/s43094-024-00680-8