Variation in blood microbial lipopolysaccharide (LPS) contributes to immune reconstitution in response to suppressive antiretroviral therapy in HIV

Variation in blood microbial lipopolysaccharide (LPS) contributes to immune reconstitution in response to suppressive antiretroviral therapy in HIV

Summary: Background: In HIV infection, even under long-term antiretroviral therapy (ART), up to 20% of HIV-infected individuals fail to restore CD4+ T cell counts to the levels similar to those of healthy controls. The mechanisms of poor CD4+ T cell reconstitution on suppressive ART are not fully u...

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Bibliographic Details
Main Authors: Zhenwu Luo, Sonya L. Health, Min Li, Hyojik Yang, Yongxia Wu, Michael Collins, Steven G. Deeks, Jeffrey N. Martin, Alison Scott, Wei Jiang
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:EBioMedicine
Subjects:
HIV
Immune non-responders
Immune responders
Lipopolysaccharide
Lipid A
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422002183

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http://www.sciencedirect.com/science/article/pii/S2352396422002183

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