How to Obtain a Mega-Intestine with Normal Morphology: In Silico Modelling of Postnatal Intestinal Growth in a Cd97-Transgenic Mouse

How to Obtain a Mega-Intestine with Normal Morphology: In Silico Modelling of Postnatal Intestinal Growth in a Cd97-Transgenic Mouse

Intestinal cylindrical growth peaks in mice a few weeks after birth, simultaneously with crypt fission activity. It nearly stops after weaning and cannot be reactivated later. Transgenic mice expressing <i>Cd97</i>/<i>Adgre5</i> in the intestinal epithelium develop a mega-int...

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Bibliographic Details
Main Authors: Felix Hofmann, Torsten Thalheim, Karen Rother, Marianne Quaas, Christiane Kerner, Jens Przybilla, Gabriela Aust, Joerg Galle
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
mega-intestine
postnatal development
crypt formation
Cd97
Klf4
Areg
Online Access:https://www.mdpi.com/1422-0067/22/14/7345

Internet

https://www.mdpi.com/1422-0067/22/14/7345

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