Homologous Recombination Deficiency Score Determined by Genomic Instability in a Romanian Cohort

Homologous Recombination Deficiency Score Determined by Genomic Instability in a Romanian Cohort

The Homologous Recombination Deficiency (HRD) Score, determined by evaluating genomic instability through the assessment of loss of heterozygosity (LOH), telomeric allelic imbalance (TAI), and large-scale state transitions (LST), serves as a crucial biomarker for identifying patients who might benef...

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Bibliographic Details
Main Authors: Viorica-Elena Rădoi, Mihaela Țurcan, Ovidiu Virgil Maioru, Andra Dan, Laurentiu Camil Bohîlțea, Elena Adriana Dumitrescu, Adelina Silvana Gheorghe, Dana Lucia Stănculeanu, Georgia Thodi, Yannis L. Loukas, Ileana-Delia Săbău
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Diagnostics
Subjects:
homologous recombination deficiency
Romanian cohort
ovarian cancer
Online Access:https://www.mdpi.com/2075-4418/13/11/1896

Internet

https://www.mdpi.com/2075-4418/13/11/1896

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