Albumin induces upregulation of matrix metalloproteinase-9 in astrocytes via MAPK and reactive oxygen species-dependent pathways

Albumin induces upregulation of matrix metalloproteinase-9 in astrocytes via MAPK and reactive oxygen species-dependent pathways

<p>Abstract</p> <p>Background</p> <p>Astrocytes are an integral component of the blood–brain barrier (BBB) which may be compromised by ischemic or traumatic brain injury. In response to trauma, astrocytes increase expression of the endopeptidase matrix metalloproteinase...

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Bibliographic Details
Main Authors: Ranaivo Hantamalala, Hodge Jessica N, Choi Nicole, Wainwright Mark S
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Journal of Neuroinflammation
Subjects:
Matrix metalloproteinase
Astrocyte
Blood brain barrier
Mitogen-activated protein kinases
Online Access:http://www.jneuroinflammation.com/content/9/1/68

Internet

http://www.jneuroinflammation.com/content/9/1/68

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