A novel regulated network mediated by downregulation HIF1A-AS2 lncRNA impairs placental angiogenesis by promoting ANGPTL4 expression in preeclampsia

A novel regulated network mediated by downregulation HIF1A-AS2 lncRNA impairs placental angiogenesis by promoting ANGPTL4 expression in preeclampsia

Preeclampsia (PE) is the predominant medical condition leading to maternal and fetal mortality, and the lack of effective treatment increases its risk to the public health. Among the numerous predisposing factors, the ineffectual remodeling of the uterine spiral arteries, which can induce abnormal p...

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Bibliographic Details
Main Authors: Lijun Shu, Cong Wang, Zhengzheng Ding, Jianjiao Tang, Yuanyuan Zhu, Liuxin Wu, Zheyue Wang, Tingting Zhang, Tianjun Wang, Yetao Xu, Lizhou Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
preeclampsia
lncRNA
HIF1A-AS2
placental angiogenesis
ANGPTL4
LNMA
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.837000/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.837000/full

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