Formulation of Enalapril Maleate Nanoproniosomal Gels and Their Pharmacokinetic Evaluations in Hypertensive Albino Wistar Rats: Ex Vivo and In Vivo Approaches

Formulation of Enalapril Maleate Nanoproniosomal Gels and Their Pharmacokinetic Evaluations in Hypertensive Albino Wistar Rats: Ex Vivo and In Vivo Approaches

Proniosomes are drug-encapsulated, nanoscale vesicular structures that generate multilamellar niosomal dispersions upon hydration. This study aimed to develop enalapril maleate nanoproniosomal gels and assess their effectiveness in experimental hypertensive rat models. The gels were synthesized base...

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Bibliographic Details
Main Authors: Mekala Sabareesh, Jayaraman Rajangam, Janapati Pedda Yanadaiah
Format: Article
Language:English
Published: Tsinghua University Press 2024-09-01
Series:Nano Biomedicine and Engineering
Subjects:
enalapril maleate
proniosomes
ex vivo permeation
in vivo antihypertensive research
in vivo bio-availability investigation
pharmacokinetic research
in vitro–in vivo correlation
Online Access:https://www.sciopen.com/article/10.26599/NBE.2024.9290084

Internet

https://www.sciopen.com/article/10.26599/NBE.2024.9290084

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