Implementing patient derived organoids in functional precision medicine for patients with advanced colorectal cancer

Implementing patient derived organoids in functional precision medicine for patients with advanced colorectal cancer

Abstract Background Patient Derived Organoids (PDOs) emerged as the best technology to develop ex vivo tumor avatars. Whether drug testing on PDOs to identify efficient therapies will bring clinical utility by improving patient survival remains unclear. To test this hypothesis in the frame of clinic...

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Bibliographic Details
Main Authors: Jérôme Cartry, Sabrina Bedja, Alice Boilève, Jacques R. R. Mathieu, Emilie Gontran, Maxime Annereau, Bastien Job, Ali Mouawia, Pierre Mathias, Thierry De Baère, Antoine Italiano, Benjamin Besse, Isabelle Sourrouille, Maximiliano Gelli, Mohamed-Amine Bani, Peggy Dartigues, Antoine Hollebecque, Cristina Smolenschi, Michel Ducreux, David Malka, Fanny Jaulin
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Organoids
Precision medicine
Colorectal cancer
Chemogram
Online Access:https://doi.org/10.1186/s13046-023-02853-4

Internet

https://doi.org/10.1186/s13046-023-02853-4

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