ROCker Models for Reliable Detection and Typing of Short-Read Sequences Carrying β-Lactamase Genes

ROCker Models for Reliable Detection and Typing of Short-Read Sequences Carrying β-Lactamase Genes

ABSTRACT Identification of genes encoding β-lactamases (BLs) from short-read sequences remains challenging due to the high frequency of shared amino acid functional domains and motifs in proteins encoded by BL genes and related non-BL gene sequences. Divergent BL homologs can be frequently missed du...

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Bibliographic Details
Main Authors: Si-Yu Zhang, Brittany Suttner, Luis M. Rodriguez-R, Luis H. Orellana, Roth E. Conrad, Fang Liu, Jessica L. Rowell, Hattie E. Webb, Amanda J. Williams-Newkirk, Andrew Huang, Konstantinos T. Konstantinidis
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mSystems
Subjects:
β-lactamases
short reads
ROCker models
high F1 score
Online Access:https://journals.asm.org/doi/10.1128/msystems.01281-21

Internet

https://journals.asm.org/doi/10.1128/msystems.01281-21

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