Vasovasostomy and vasoepididymostomy: Review of the procedures, outcomes, and predictors of patency and pregnancy over the last decade

Abstract Background In the era of improving assisted reproductive technology (ART), patients with obstructive azoospermia (OA) have 2 options: vasal repair or testicular sperm extraction with intracytoplasmic sperm injection. Vasal repair, including vasovasostomy (VV) and vasoepididymostomy (VE), is...

Full description

Bibliographic Details
Main Authors: Takeshi Namekawa, Takashi Imamoto, Mayuko Kato, Akira Komiya, Tomohiko Ichikawa
Format: Article
Language:English
Published: Wiley 2018-10-01
Series:Reproductive Medicine and Biology
Subjects:
Online Access:https://doi.org/10.1002/rmb2.12207
_version_ 1819176942706884608
author Takeshi Namekawa
Takashi Imamoto
Mayuko Kato
Akira Komiya
Tomohiko Ichikawa
author_facet Takeshi Namekawa
Takashi Imamoto
Mayuko Kato
Akira Komiya
Tomohiko Ichikawa
author_sort Takeshi Namekawa
collection DOAJ
description Abstract Background In the era of improving assisted reproductive technology (ART), patients with obstructive azoospermia (OA) have 2 options: vasal repair or testicular sperm extraction with intracytoplasmic sperm injection. Vasal repair, including vasovasostomy (VV) and vasoepididymostomy (VE), is the only option that leads to natural conception. Methods This article reviews the surgical techniques, outcomes, and predictors of postoperative patency and pregnancy, with a focus on articles that have reported over the last 10 years, using PubMed database searches. Main findings The reported mean patency rate was 87% and the mean pregnancy rate was 49% for a patient following microscopic VV and/or VE for vasectomy reversal. Recently, robot‐assisted techniques were introduced and have achieved a high rate of success. The predictors and predictive models of postoperative patency and pregnancy also have been reported. The obstructive interval, presence of a granuloma, and intraoperative sperm findings predict postoperative patency. These factors also predict postoperative fertility. In addition, the female partner's age and the same female partner correlate with pregnancy after surgery. Conclusion In the era of ART, the physician should present and discuss with both the patient with OA and his partner the most appropriate procedure to conceive by using these predictors.
first_indexed 2024-12-22T21:18:47Z
format Article
id doaj.art-0d8bdbc9af404112a9d8791860d1436b
institution Directory Open Access Journal
issn 1445-5781
1447-0578
language English
last_indexed 2024-12-22T21:18:47Z
publishDate 2018-10-01
publisher Wiley
record_format Article
series Reproductive Medicine and Biology
spelling doaj.art-0d8bdbc9af404112a9d8791860d1436b2022-12-21T18:12:15ZengWileyReproductive Medicine and Biology1445-57811447-05782018-10-0117434335510.1002/rmb2.12207Vasovasostomy and vasoepididymostomy: Review of the procedures, outcomes, and predictors of patency and pregnancy over the last decadeTakeshi Namekawa0Takashi Imamoto1Mayuko Kato2Akira Komiya3Tomohiko Ichikawa4Department of Urology Graduate School of Medicine Chiba University Chiba JapanDepartment of Urology Graduate School of Medicine Chiba University Chiba JapanDepartment of Urology Graduate School of Medicine Chiba University Chiba JapanDepartment of Urology Graduate School of Medicine Chiba University Chiba JapanDepartment of Urology Graduate School of Medicine Chiba University Chiba JapanAbstract Background In the era of improving assisted reproductive technology (ART), patients with obstructive azoospermia (OA) have 2 options: vasal repair or testicular sperm extraction with intracytoplasmic sperm injection. Vasal repair, including vasovasostomy (VV) and vasoepididymostomy (VE), is the only option that leads to natural conception. Methods This article reviews the surgical techniques, outcomes, and predictors of postoperative patency and pregnancy, with a focus on articles that have reported over the last 10 years, using PubMed database searches. Main findings The reported mean patency rate was 87% and the mean pregnancy rate was 49% for a patient following microscopic VV and/or VE for vasectomy reversal. Recently, robot‐assisted techniques were introduced and have achieved a high rate of success. The predictors and predictive models of postoperative patency and pregnancy also have been reported. The obstructive interval, presence of a granuloma, and intraoperative sperm findings predict postoperative patency. These factors also predict postoperative fertility. In addition, the female partner's age and the same female partner correlate with pregnancy after surgery. Conclusion In the era of ART, the physician should present and discuss with both the patient with OA and his partner the most appropriate procedure to conceive by using these predictors.https://doi.org/10.1002/rmb2.12207male infertilityobstructive azoospermiavasectomy reversalvasoepididymostomyvasovasostomy
spellingShingle Takeshi Namekawa
Takashi Imamoto
Mayuko Kato
Akira Komiya
Tomohiko Ichikawa
Vasovasostomy and vasoepididymostomy: Review of the procedures, outcomes, and predictors of patency and pregnancy over the last decade
Reproductive Medicine and Biology
male infertility
obstructive azoospermia
vasectomy reversal
vasoepididymostomy
vasovasostomy
title Vasovasostomy and vasoepididymostomy: Review of the procedures, outcomes, and predictors of patency and pregnancy over the last decade
title_full Vasovasostomy and vasoepididymostomy: Review of the procedures, outcomes, and predictors of patency and pregnancy over the last decade
title_fullStr Vasovasostomy and vasoepididymostomy: Review of the procedures, outcomes, and predictors of patency and pregnancy over the last decade
title_full_unstemmed Vasovasostomy and vasoepididymostomy: Review of the procedures, outcomes, and predictors of patency and pregnancy over the last decade
title_short Vasovasostomy and vasoepididymostomy: Review of the procedures, outcomes, and predictors of patency and pregnancy over the last decade
title_sort vasovasostomy and vasoepididymostomy review of the procedures outcomes and predictors of patency and pregnancy over the last decade
topic male infertility
obstructive azoospermia
vasectomy reversal
vasoepididymostomy
vasovasostomy
url https://doi.org/10.1002/rmb2.12207
work_keys_str_mv AT takeshinamekawa vasovasostomyandvasoepididymostomyreviewoftheproceduresoutcomesandpredictorsofpatencyandpregnancyoverthelastdecade
AT takashiimamoto vasovasostomyandvasoepididymostomyreviewoftheproceduresoutcomesandpredictorsofpatencyandpregnancyoverthelastdecade
AT mayukokato vasovasostomyandvasoepididymostomyreviewoftheproceduresoutcomesandpredictorsofpatencyandpregnancyoverthelastdecade
AT akirakomiya vasovasostomyandvasoepididymostomyreviewoftheproceduresoutcomesandpredictorsofpatencyandpregnancyoverthelastdecade
AT tomohikoichikawa vasovasostomyandvasoepididymostomyreviewoftheproceduresoutcomesandpredictorsofpatencyandpregnancyoverthelastdecade