Protective effects of Radix Stellariae extract against Alzheimer's disease via autophagy activation in Caenorhabditis elegans and cellular models

Protective effects of Radix Stellariae extract against Alzheimer's disease via autophagy activation in Caenorhabditis elegans and cellular models

Enhancing the clearance of proteins associated with Alzheimer's disease (AD) emerges as a promising approach for AD therapeutics. This study explores the potential of Radix Stellariae, a traditional Chinese medicine, in treating AD. Utilizing transgenic C. elegans models of AD, we demonstrated...

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Bibliographic Details
Main Authors: Tao Long, Xue Chen, Yue Zhang, Yu-Jia Zhou, Yan-Ni He, Yun-Fei Zhu, Hai-Jun Fu, Lu Yu, Chong-Lin Yu, Betty Yuen-Kwan Law, Jian-Ming Wu, Da-Lian Qin, An-Guo Wu, Xiao-Gang Zhou
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Alzheimer’s disease
Radix Stellariae
Autophagy
C. elegans
PC-12 cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223010521

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http://www.sciencedirect.com/science/article/pii/S0753332223010521

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