Selective Pressure for Biofilm Formation in <named-content content-type="genus-species">Bacillus subtilis</named-content>: Differential Effect of Mutations in the Master Regulator SinR on Bistability

Selective Pressure for Biofilm Formation in <named-content content-type="genus-species">Bacillus subtilis</named-content>: Differential Effect of Mutations in the Master Regulator SinR on Bistability

ABSTRACT Biofilm formation by Bacillus subtilis requires the expression of genes encoding enzymes for extracellular polysaccharide synthesis and for an amyloid-like protein. The master regulator SinR represses all the corresponding genes, and repression of these key biofilm genes is lifted when SinR...

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Bibliographic Details
Main Authors: Jan Kampf, Jan Gerwig, Kerstin Kruse, Robert Cleverley, Miriam Dormeyer, Alexander Grünberger, Dietrich Kohlheyer, Fabian M. Commichau, Richard J. Lewis, Jörg Stülke
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
biofilm formation
bistability
gene expression
microfluidics
suppressor mutants
Online Access:https://journals.asm.org/doi/10.1128/mBio.01464-18

Internet

https://journals.asm.org/doi/10.1128/mBio.01464-18

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