Role of Age-Related Changes in DNA Methylation in the Disproportionate Susceptibility and Worse Outcomes of Sepsis in Older Adults

Role of Age-Related Changes in DNA Methylation in the Disproportionate Susceptibility and Worse Outcomes of Sepsis in Older Adults

Sepsis, a complex multisystem disorder, is among the top causes of hospitalization and mortality in older adults. However, the mechanisms underlying the disproportionate susceptibility to sepsis and worse outcomes in the elderly are not well understood. Recently, changes in DNA methylation have been...

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Bibliographic Details
Main Authors: Xiabing Lang, Lingling Shen, Tingting Zhu, Wenjun Zhao, Yang Chen, Chaohong Zhu, Qun Su, Cuili Wang, Yucheng Wang, Francesco Neri, Hong Jiang, Jianghua Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Medicine
Subjects:
sepsis
DNA methylation
aging
susceptibility
outcomes
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.822847/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.822847/full

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