Signals of historical interlocus gene conversion in human segmental duplications.

Standard methods of DNA sequence analysis assume that sequences evolve independently, yet this assumption may not be appropriate for segmental duplications that exchange variants via interlocus gene conversion (IGC). Here, we use high quality multiple sequence alignments from well-annotated segmenta...

Full description

Bibliographic Details
Main Authors: Beth L Dumont, Evan E Eichler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790853?pdf=render