Retrospective analysis of 60 patients with Hemophagocytic Lymphohistiocytosis (HLH): focus on genetic variants associated with secondary/late onset disease

Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder of uncontrolled cytotoxic T-lymphocyte and macrophage activation associated with extreme inflammation, which if left untreated is invariably fatal. HLH can be classified either as primary (familial) or secondary (acquired). Genetic mutation...

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Bibliographic Details
Main Authors: Meeta Sunil, Chirantan Bose, Coral Karunakaran, Sunil Bhat, Nita Radhakrishnan, Srisha Rani, Saktivel Murugan, Ravi Gupta, Rohit Gupta, Mukesh Desai, Arati Khanna- Gupta
Format: Article
Language:English
Published: Science Planet Inc. 2017-12-01
Series:Canadian Journal of Biotechnology
Online Access:https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue-Supplement/cjb.2017-a237.pdf