UHRF2 regulates local 5-methylcytosine and suppresses spontaneous seizures

The 5-methylcytosine (5mC) modification regulates multiple cellular processes and is faithfully maintained following DNA replication. In addition to DNA methyltransferase (DNMT) family proteins, ubiquitin-like PHD and ring finger domain-containing protein 1 (UHRF1) plays an important role in the mai...

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Bibliographic Details
Main Authors: Yidan Liu, Bin Zhang, Xiaoyu Meng, Matthew J. Korn, Jack M. Parent, Lin-Yu Lu, Xiaochun Yu
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2017.1314423