Astragalus polysaccharides ameliorate epileptogenesis, cognitive impairment, and neuroinflammation in a pentylenetetrazole-induced kindling mouse model

Astragalus polysaccharides ameliorate epileptogenesis, cognitive impairment, and neuroinflammation in a pentylenetetrazole-induced kindling mouse model

Background: Epilepsy is a prevalent neurological disease where neuroinflammation plays a significant role in epileptogenesis. Recent studies have suggested that Astragalus polysaccharides (APS) have anti-inflammatory properties, which make them a potential candidate for neuroprotection against centr...

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Bibliographic Details
Main Authors: Yuling Lu, Minglin Lin, Sijie Ou, Lanfeng Sun, Kai Qian, Huimin Kuang, Yuan Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Pharmacology
Subjects:
Astragalus polysaccharides
epilepsy
cognitive deficit
network pharmacology
TLR4/NF-κB
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1336122/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1336122/full

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