A hyperoxic lung injury model in premature rabbits: the influence of different gestational ages and oxygen concentrations.

BACKGROUND: Many animal models have been developed to study bronchopulmonary dysplasia (BPD). The preterm rabbit is a low-cost, easy-to-handle model, but it has a high mortality rate in response to the high oxygen concentrations used to induce lung injury. The aim of this study was to compare the mo...

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Bibliographic Details
Main Authors: Roberta Munhoz Manzano, Renata Suman Mascaretti, Valéria Carrer, Luciana Branco Haddad, Aline Rabelo Fernandes, Ana M A Reyes, Celso Moura Rebello
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3995887?pdf=render