Extracellular Vesicles Secreted by Hypoxic AC10 Cardiomyocytes Modulate Fibroblast Cell Motility

Extracellular Vesicles Secreted by Hypoxic AC10 Cardiomyocytes Modulate Fibroblast Cell Motility

Extracellular vesicles (EVs) are small membrane vesicles secreted by most cell types with important roles in cell-to-cell communication. To assess their relevance in the context of heart ischemia, EVs isolated from the AC10 ventricular cardiomyocyte cell line (CM-EVs), exposed to normoxia (Nx) or hy...

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Bibliographic Details
Main Authors: Imelda Ontoria-Oviedo, Akaitz Dorronsoro, Rafael Sánchez, Maria Ciria, Marta Gómez-Ferrer, Marc Buigues, Elena Grueso, Sandra Tejedor, Francisco García-García, Hernán González-King, Nahuel A. Garcia, Esteban Peiró-Molina, Pilar Sepúlveda
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
cardiomyocytes
fibroblasts
endothelial cells
extracellular vesicles
hypoxia
cellular communication
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00152/full

Internet

https://www.frontiersin.org/article/10.3389/fcvm.2018.00152/full

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