Oncolytic Replication of E1b-Deleted Adenoviruses

Various viruses have been studied and developed for oncolytic virotherapies. In virotherapy, a relatively small amount of viruses used in an intratumoral injection preferentially replicate in and lyse cancer cells, leading to the release of amplified viral particles that spread the infection to the...

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Bibliographic Details
Main Authors: Pei-Hsin Cheng, Stephen L. Wechman, Kelly M. McMasters, Heshan Sam Zhou
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/7/11/2905