CircMMP11 overexpression predicts the poor survival of non-small cell lung cancer and downregulates miR-143 through methylation to suppress cell proliferation

Abstract Background CircMMP11 is a characterized circRNA with oncogenic function in breast cancer. In this study, we explored the involvement of circMMP11 in non-small cell lung cancer (NSCLC). Methods Paired cancer and non-cancer tissues were collected from 66 NSCLC patients, and the expression of...

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Bibliographic Details
Main Authors: Juan Chen, Jiang Gong
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Online Access:https://doi.org/10.1186/s13019-021-01701-w