Exploring the safety and efficacy of phytomedicine Petiveria alliacea extract (Esperanza) in patients with metastatic gastrointestinal tumors and acute leukemias: study protocol for a phase Ib/randomized double blind phase II trial (PA001)

Exploring the safety and efficacy of phytomedicine Petiveria alliacea extract (Esperanza) in patients with metastatic gastrointestinal tumors and acute leukemias: study protocol for a phase Ib/randomized double blind phase II trial (PA001)

Abstract Background The energy metabolism of drug-resistant tumor cells can provide a survival advantage during therapy, and treatment itself may influence metabolic reprogramming. Petiveria alliacea (Traditional name: Anamu) could inhibit glycolysis and OXPHOX modulating tumor metabolism, making it...

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Bibliographic Details
Main Authors: Ricardo Ballesteros-Ramírez, Paola Pinilla, Jesús Sanchéz, Mónica Arévalo, Elio Sanchez, Pablo Aschner, Claudia Urueña, Susana Fiorentino
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Petiveria alliacea
Herbal Drugs
Safety
Efficacy
Tumoral metabolism
Quality of Life
Online Access:https://doi.org/10.1186/s12906-023-04109-2

Internet

https://doi.org/10.1186/s12906-023-04109-2

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