Suppressing MTERF3 inhibits proliferation of human hepatocellular carcinoma via ROS-mediated p38 MAPK activation

Suppressing MTERF3 inhibits proliferation of human hepatocellular carcinoma via ROS-mediated p38 MAPK activation

Abstract Mitochondrial transcription termination factor 3 (MTERF3) negatively regulates mitochondrial DNA transcription. However, its role in hepatocellular carcinoma (HCC) progression remains elusive. Here, we investigate the expression and function of MTERF3 in HCC. MTERF3 is overexpressed in HCC...

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Bibliographic Details
Main Authors: Zhihai Zheng, Youjuan Zhao, Hongjia Yu, Tingting Wang, Jinhai Li, Liang Xu, Chunming Ding, Lan He, Lijun Wu, Zhixiong Dong
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05664-7

Internet

https://doi.org/10.1038/s42003-023-05664-7

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