In silico Prediction, Characterization, Molecular Docking, and Dynamic Studies on Fungal SDRs as Novel Targets for Searching Potential Fungicides Against Fusarium Wilt in Tomato

In silico Prediction, Characterization, Molecular Docking, and Dynamic Studies on Fungal SDRs as Novel Targets for Searching Potential Fungicides Against Fusarium Wilt in Tomato

Vascular wilt of tomato caused by Fusarium oxysporum f.sp. lycopersici (FOL) is one of the most devastating diseases, that delimits the tomato production worldwide. Fungal short-chain dehydrogenases/reductases (SDRs) are NADP(H) dependent oxidoreductases, having shared motifs and common functional m...

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Bibliographic Details
Main Authors: Mohd Aamir, Vinay Kumar Singh, Manish Kumar Dubey, Mukesh Meena, Sarvesh Pratap Kashyap, Sudheer Kumar Katari, Ram Sanmukh Upadhyay, Amineni Umamaheswari, Surendra Singh
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
THN reductase
fungicide
melanin
protein–fungicide interaction
homology modeling
MD simulations
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01038/full

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https://www.frontiersin.org/article/10.3389/fphar.2018.01038/full

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